Duggan Veterinary Supplies is delighted to promote an innovative, easy-to-use and cost-effective treatment for gastric ulcers in horses from their established equine healthcare range.
EquizolTM contains gastro-resistant omeprazole granules for infeed administration, providing a convenient, effective and proven method of treating gastric ulcers in horses. Omeprazole, an acid-pump inhibitor five times more potent than ranitidine, has been used with great success to help improve healing and prevent the development and recurrence of gastric ulcers 1,2
Equine Gastric Ulcer Syndrome (EGUS) is very common among horses with a reported prevalence of approximately 90%4 of Thoroughbred horses in racing and training, 83.5% in performance horses and >50% in young stock and leisure horses3.
Previous studies done comparing enteric coated omeprazole to the buffered pastes have found no statistically significant differences in bioavailability3.
Managing Director Donal Duggan is delighted to have a product such as EquizolTM in the equine armoury stating: ‘It is widely accepted that gastric ulcers can affect performance. EquizolTM is available in 400mg sachets and is for oral administration. Each sachet is sufficient to treat 200kg bodyweight, at the recommended dose of 2mg/kg per day for 28 days.’
In a recently published study by Barton et al (2022) EquizolTM was compared to a leading buffered omeprazole paste in the treatment of horses diagnosed with ESGD (Equine Squamous Gastric Disease) and in combination with sucralfate in horses diagnosed with EGGD (Equine Glandular Gastric Disease)5. EquizolTM was shown to be highly effective in improving both ESGD and EGGD scores with no significant differences between EquizolTM and the buffered formulation. The authors concluded that EquizolTM can be recommended for the treatment of EGUS in particular ESGD5.
For more information, contact sales@dugganvet.ie.
1 Sykes, B.W et al (2015) ‘A comparison of three doses of omeprazole in the treatment of equine gastric ulcer syndrome: a blinded, randomised, dose-response clinical trial’ Equine Veterinary Journal, 47, pp285-290
2 Mason, L.V et al (2019) ‘Prophylactic therapy with omeprazole for prevention of equine gastric ulcer syndrome in horses in active training: A met-analysis’ Equine Veterinary Journal, 51, pp 11- 19)
3 Sykes, B.W et al (2015) ‘European College of Equine Internal Medicine Consensus Statement- Equine Gastric Ulcer Syndrome in Adult Horses’ Journal of Veterinary Internal Medicine, 29, pp 1288-1299
4 Johnson, J.H et al (2001) ‘Field survey of the prevalence of gastric ulcers in Thoroughbred racehorses and on response to treatment of affected horses with omeprazole paste’ Equine Veterinary Education, 13(4), pp221-2244
5 Barton, A.K et al (2022) ‘Efficacy of two oral omeprazole formulations for the therapy of equine gastric ulcer syndrome (EGUS)’ Pfredeheilkunde – Equine Medicine, 38, pp118-126
